The first group is the studies that described the generation of patient-specific iPSC lines [43,44,45,46,47,48,49,50,51,52,53,54,55,56] that carry genetic variants in genes associated with epilepsy, such as SCN1A, GNB5, LGI1, GRIN2A, KCNC1, or KCNA2 (Figure 3, Table S1) [43,44,45,46,47,48,49,50,51,52,53,54,55,56]. Here, GNB5 is linked to epilepsy.