In the ovarian cancer cell group, NS cell lines (A2780 and SKOV3 cells) revealed an AKR1B1 protein higher than the high-grade serous ovarian cancer cell lines (OVCAR3 cells), and SKOV3 cells showed the highest AKR1B1 level (Figure 1A,B and Figure S1). This evidence concerns the gene AKR1B1 and ovarian serous adenocarcinoma.