The IL-33-mediated inhibition of atherosclerosis-associated genes, like MCP-1 and ICAM-1 (intercellular adhesion molecule 1), was also reported in the macrophages, and this anti-atherogenic action of IL-33 involved various signaling pathways, i.e., p38α, ERK1/2, JNK1/2, PI3Kγ, and NF-κB [42]. Here, CCL2 is linked to atherosclerosis.