For example, cardamonin, a natural flavone isolate from Alpinia katsumadai Hayata [32], dehydroepiandrosterone, a popular dietary supplement [33], and palmatine, an isoquinoline alkaloid isolated from the traditional herb Fibraurea Recisa Pierre [34] attenuated IBD by inhibiting the NLRP3 inflammasome in mice. This evidence concerns the gene NLRP3 and inflammatory bowel disease.