IGFBP2 and diabetes mellitus: Correlations between litter size and body traits have been reported in goats [21], and genes have been found to affect both litter size and growth, in many cases: for example, IGF2-BP2 (insulin-like growth factor 2 mRNA-binding protein 2) plays a key role in the development of diabetes and animal growth and is also a candidate gene for litter size in goats [34].