Although the adipocytes (a marker of ARVC) were not increased in the RV under the influence of VO (Figure 9A), the lipid metabolism enzyme long-chain acyl-CoA synthetase 1 (ACSL1) was significantly increased in the RV (Figure 9B,C). The gene discussed is ACSL1; the disease is arrhythmogenic right ventricular cardiomyopathy.