In order to explore whether CYA can effectively reduce androgen levels and alleviate the occurrence of ovarian GC pyroptosis in PCOS patients, three animal models were constructed in this study—the PCOS group, the treatment group and the control group—to detect the expression of pyroptosis-related proteins, TT, IL-18, IL-1β, and the NLRP3 inflammasome. This evidence concerns the gene IL18 and polycystic ovary syndrome.