CDKN2A and lung cancer: In Canada, Yanagawa et al., 2013, reported HPV incidences in five out of three hundred and thirty-six (1.5%) lung cancers by using ISH and PCR [129], while Chang et al. (2015) reported negative results in 196 lung cancer samples by conducting ISH, an HR-HPV E6/E7 RNA detection and p16 IHC [130].