Additionally, PP was correlated with ΔMMSE in Model 2 after adjusting for education, lack of physical exercise, smoking, drinking, diabetes, cardiovascular disease, dyslipidemia, APOE ε4 carriage and MAP (b = 0.021, t = 2.339, p = 0.019), and in Model 3, where MAP was replaced with hypertension (b = 0.021, t = 2.323, p = 0.020). Here, APOE is linked to cardiovascular disorder.