APOE and cardiovascular disorder: After further adjusting for education, lack of physical exercise, smoking, drinking, diabetes, cardiovascular disease, dyslipidemia, APOE ε4 carriage and MAP in Model 2 (OR = 1.019, 95% CI 1.001–1.037, p = 0.035) and replacing MAP with hypertension in Model 3, the effects remained significant (OR = 1.020, 95% CI 1.003–1.038, p = 0.023) (Table 3).