First defined in 2016 [1], autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is a corticosteroid-responsive inflammatory central nervous system (CNS) disorder spectrum, predominantly affecting the meninges, brain, spinal cord, and optic nerves with manifestations of fever, headaches, tremors, ataxia, encephalopathy, myelitis, involuntary movement, and abnormal vision, mimicking infectious meningoencephalitis [2,3]. The gene discussed is GFAP; the disease is Encephalopathy.