YAP1 and autoimmune polyendocrinopathy: Considering the anti-β2GPI antibody, among all subtypes of anti-phospholipid antibodies, is one of the most frequently used prognostic indices for pregnancy morbidity in APS patients [14], we further found that the aβ2GPI-IgG/β2GPI complex reveals dose-dependent characteristics in reducing YAP expression and nuclear localization.