IL8 has been associated with decreased depression in females and non-significant results in males within civilian non-TBI samples [18]; however, other studies have found that SMVs who met the criteria for depression 12 months after sustaining a TBI had higher levels of IL8 compared to SMVs who had sustained TBI but did not meet criteria for depression [19]. The gene discussed is CXCL8; the disease is depressive disorder.