The transcriptomic analysis by Sen et al. [26] describes periostin as the most expressed matricellular protein in MN, as these proteins were highly expressed on progressive proteinuric glomerular diseases, such as focal segmental glomerular sclerosis (FSGS) and MN, and relatively low or absent in non-progressive nephropathies, such as minimal change disease (MCD). This evidence concerns the gene POSTN and focal segmental glomerulosclerosis.