Korfiatis et al. [124] performed a large radiomic retrospective study enrolling 155 GBM patients with known MGMT methylation status, and compared several different classes of texture features, showing that the combination of four texture features (correlation, energy, entropy, and local intensity) provided a really valid potential tool for the prediction of the MGMT methylation status in GBM. This evidence concerns the gene MGMT and glioblastoma.