Additionally, serum TIMP1 showed significantly decreased activity not only in viral hepatitis (342.49 ± 184.53 ng/mL, p < 0.0001) and viral cirrhosis (485.64 ± 116.27 ng/mL, p < 0.0001) but also in alcoholic hepatitis (467.82 ± 129.75 ng/mL, p < 0.0001) and alcoholic cirrhosis (761.9 ± 241.76 ng/mL, p = 0.03) when compared to normals. The gene discussed is TIMP1; the disease is animal viral hepatitis.