Additionally, serum MMP-1 showed significantly decreased activity not only in viral hepatitis (58.47 ± 44.59 ng/mL, p < 0.05) and viral cirrhosis (52.41 ± 39.72 ng/mL, p = 0.03) but also in alcoholic hepatitis (61.42 ± 29.05 ng/mL, p = 0.05) and alcoholic cirrhosis (50.45 ± 28.14 ng/mL, p = 0.02) compared to normals. The gene discussed is MMP1; the disease is alcoholic hepatitis.