Human thyroid carcinoma tissue has also been reported to express MMP-1, MMP-2, and MMP-9 and these MMPs were localized in tumor cells and/or in the fibroblasts adjacent to or close to the invading tumor cells [19,20,21,22,23,24,25,26,27,28,29,30,31,32]. This evidence concerns the gene MMP2 and neoplasm.