The CoRegNet library generated a lung cancer coregulatory network with the gene expression levels of the GSE19804 dataset to assess the importance of the six transcriptional regulators found in the NSCLC-GRN in lung cancer establishment and progression and to identify a transcriptional regulator capable of participating as a coregulator of the tumor process via functional association with the most critical TFs identified in the gene coexpression network analysis [12]. This evidence concerns the gene GRN and lung cancer.