RUNX2 and pulmonary arterial hypertension: FOXF1 is a negatively regulated TF in eight datasets of lung cancer and in the PAH dataset [12], which appear to be coexpressed in the LCII network (Table 1) [31]; meanwhile, E2F3 is overregulated in seven datasets of lung cancer [12] and is one of the six important transcriptional regulators identified with RUNX2 in the NSCLC-GRN (Figure 1).