EMR1-TC was significantly correlated with tumor stage (T_stage, p = 0.044), LNM (p = 0.001), and lymphatic invasion (p = 0.030) in MSI-H CRC, while MSS CRC showed significant correlation only in LNM (p = 0.037) among all clinicopathological parameters. This evidence concerns the gene ADGRE1 and colorectal carcinoma.