In a mouse AD model using a knockout of the protein translocator protein 18 kDa, a molecular sensor specific to glial cells in the brain, it was shown that there is increased Aβ deposition in the brain and a decreased number of microglia undergoing phagocytosis compared to control mice [113], highlighting the importance of effective microglial phagocytosis in the prevention of AD. Here, TSPO is linked to Alzheimer disease.