The same correlation (between Ald and renin) was observed in patients with HT, after excluding those with beta-blocker therapy: Spearman’s r = 0.73, p = 0.006 (n = 16), as well as after excluding seven subjects with Ald < 3 ng/dL and/or DRC above the upper reference range: r = 0.4, p = 0.048 (n = 30). The gene discussed is REN; the disease is hematocrit.