ELN and triple-A syndrome: AAA is an atherothrombotic and inflammatory disease characterized by an irreversible aortic wall remodelling and by the presence of: (1) a non-occlusive intraluminal thrombus (ILT), in most patients, which participates to the progression of the aneurysm; (2) a degraded media, with loss of elastin and collagen, as well as loss of vascular smooth muscle cells (VSMCs); (3) a thicker than normal inflammatory and/or fibrotic adventitia [1,43].