The possible mechanism of these AuNPs in T1DM relies on the induction of tolerogenic responses in DC by AuNPs via induction of the suppressor of cytokine signaling 2 (Socs2), which results in the inhibition of nuclear factor κB (NF-κB) activation and proinflammatory cytokine production [55]. The gene discussed is SOCS2; the disease is type 1 diabetes mellitus.