PRODH has been involved in NSCLC metastasis as shown, both in vitro and in vivo [73,74], and ADORA1, which is highly expressed in EGFR-mutant NSCLC biopsies [75], has been associated involved in tumor-immune evasion in NSCLC xenograft models [76]. The gene discussed is EGFR; the disease is non-small cell lung carcinoma.