Analysis revealed that the IL-37 expression pattern significantly differs in various types of human cancers (one-way ANOVA p < 0.0001), whereas among the 17 types examined, lung cancer exhibited the highest IL-37 mRNA levels (mean ± SD: 6.5 ± 31.88, n = 994) (Table 1, Figure 1A). Here, IL37 is linked to lung cancer.