MERTK and neoplasm: Interestingly, Niu et al. enabled macrophages to recognise CCR7+ cells and exert cytotoxic activity through the MerTK cytosolic domain, one of the most efficient phagocytosis inducers in vitro, suppressing tumour growth in vivo with low toxicity, prolonging survival, preventing metastasis, inducing T cell infiltration, and inducing systemic anti-tumour immunity [109].