Some authors were suggested that miRNAs (for example microRNA-let-7a, miR-125b, miR-146b-3p, miR-638, miR-31, miR-218, miR-454-3p and miRNA-936) by targeting E2F2, could be influenced by cancer progression, overall survival of patients and response to radiochemotherapy. Here, E2F2 is linked to cancer.