In the time-independent study, increased expression levels of suppressor PD-L1 marker on tumour-associated myeloid-derived suppressor cells (MDSCs; CD11b+Ly-6G+Ly-6C−) was observed only in nsECT4-treated compared to untreated and μsECT-treated mice (Figure 6E). The gene discussed is ITGAM; the disease is neoplasm.