CEACAM5 and neoplasm: In multivariate analysis (n = 735 with 98 events), seven covariates with p-value < 0.05 in the univariate analyses were included, excluding thrombocytes not collected in Cohort A. Factors that were statistically significant for pCR in the multivariate model included cT1-2 (OR 3.37 with cT4 as reference), tumour length ≤ 3.5 cm (OR 2.27), non-elevated CEA (OR 1.73), and CRT (OR 2.61 with scRT as reference) or scRT/CRT + CTX (OR 4.70 with scRT as reference).