For the univariate analysis, age, gender, BMI, hypertension, cardiovascular disease, diabetes mellitus, hepatitis, chronic renal disease, tumor location, TNM stage, pT status, pN status, histologic type, histologic grade, obstruction, perforation, hemoglobin level, albumin level, and CIPI were significantly associated with RFS. The gene discussed is ALB; the disease is hepatitis A virus infection.