Moreover, circ_RNF13 and DDX27 were upregulated in the CRC cells lines CoLo205, DLD-1, HT-29, CoLo320, RKO, NCI-H716, and Caco-2 cells compared with normal colon cell line NCM-460 cells (Figure 2E,F). The gene discussed is DDX27; the disease is colorectal carcinoma.