Clinicopathological analysis of clinical tissues revealed that the loss of SSTR2 was significantly higher in diffuse-type GC (95.5%, 168/176) than that in IGC (88.9%, 160/180) (p = 0.02) and that that in EGC (96.6%, 115/119) was significantly higher than that in AGC (90.4%, 283/313) (p = 0.03) (Supplemental Table S4). Here, SSTR2 is linked to gastric cancer.