These chemicals can impact euthyroid state by several ways, including “disturbance of thyroid hormone biosynthesis through directly targeting the sodium-iodide symporter (NIS), interplaying with thyroid hormone transporters/receptors, interfering with the hypothalamic-pituitary-thyroid axis, and disrupting multiple molecular alterations associated with thyroid pathogenesis” [22]. Here, SLC5A5 is linked to thyroiditis.