The result indicated that in the sarcopenia group, we found no statistically significant difference in age, sex, cirrhosis, child-cough grade, TNM stage, BCLC stage, tumor size, tumor location, tumor differentiation, satellite lesions, microvascular invasion, ASA grade, blood loss, albumin, and AFP between laparoscopic versus open surgery (Supplementary Table S2). This evidence concerns the gene AFP and Cirrhosis.