Similarly, although we previously demonstrated reduced activation of AKT and ERK in response to MERTK inhibition in non-ETP T-ALL models [14], pAKT and pERK were not phosphorylated in PEER cells, and treatment with MRX-2843 did not affect pAKT and pERK levels in Loucy cells (data not shown). Here, AKT1 is linked to acute lymphoblastic leukemia.