To explore if the high decrease of sLex/a levels, which are E-selectin ligands involved in cancer cell metastasis, in BxPC-3 and Capan-1 Ac53FaxNeu5Ac-treated cells can lead to alterations in their E-selectin adhesion, we first evaluated their ability to adhere to rhE-selectin. The gene discussed is SELE; the disease is cancer.