SELE and neoplasm: The relevance of sialyl-Lewis antigens in the adhesion of tumor cells to E-selectin has also been shown by the invalidated expression of FUT3 in Capan-1 cells, which resulted in a reduction of sialyl-Lewis antigens and was associated to an inhibition of the E-selectin adhesion and a decrease of the metastatic power of the genetically modified cells [22].