B7-H5 (also known as V-domain immunoglobulin suppressor of T cell activation (VISTA), C10orf54, PD-1H, Gi24, and Dies1) is expressed at higher levels in cancer sections compared to non-cancer tissues, promotes tumour immune escape, associated with lymph node participation, cancer stage, and survival [185]. The gene discussed is VTCN1; the disease is cancer.