In this study, our Kaplan–Meier survival analysis showed that high expression of SOX11 was significantly correlated with poor survival in patients with ACC, KIRP, LIHC, PCPG, SARC, UCEC, KIRC, PRAD, PAAD and BRCA, including OS, PFS, DFS and DSS. Here, SOX11 is linked to adrenal cortex carcinoma.