Increased CD8+ and CD20+ in tumor islets and in stroma that surrounds cancer cells, decreased CD204+ in tumor islets, high Forkhead box P3+ (FOXP3+), increased presence of CD8+/CD204+, and high CD20+/CD204+ in stroma are considered predictive factors of tumor recurrence in the study of Sato et al., who investigated the evolution of thymic carcinomas [38]. The gene discussed is CD8A; the disease is neoplasm.