In this evaluation, we could also verify that the tumor size is significantly correlated with the presence of Th17/Th1 (CD4+ CCR6+ CCR5+ CXCR3−) and Th17 cells (CD4+ CCR6+ CCR5− CXCR3−) cells in the TME (Figure 4e,f). The gene discussed is CD4; the disease is neoplasm.