Since gnetin C showed improved pharmacokinetic parameters in mouse and human studies compared to both resveratrol and pterostilbene [35,43,44,45,46], we sought to compare, for the first time, the MTA1-targeted inhibitory efficacy of gnetin C and pterostilbene supplemented diets in a transgenic mouse model of early-stage prostate cancer. The gene discussed is MTA1; the disease is Familial prostate cancer.