CXCL12 and lung carcinoma: However, Li et al. demonstrated that MEG3 could promote angiogenesis in lung carcinoma, as it could significantly increase the expression of angiogenesis-related factors VEGFA, vascular endothelial growth factor B (VEGFB), bFGF, stromal cell-derived factor-1 (SDF-1), transforming growth factor β (TGF-β), angiogenin, and MMP-9 [75].