In oral squamous cell carcinoma (OSCC) and CML, MEG3 promoted apoptosis by sponging miR-548d-3p and miR-147, thereby promoting suppressor of cytokine signaling 5 (SOCS5) and suppressor of cytokine signaling 6 (SOCS6) expression while inhibiting the JAK-STAT signaling pathway [65,66]. This evidence concerns the gene SOCS5 and oral cavity squamous cell carcinoma.