However, in this series, compound St.7 (Figure 3) was one of the most potent compounds against MCF-7 cancer cell lines with IC50 values in the nanomolar level, and it showed the inhibition of tubulin polymerization with IC50 1.3 μM in comparison with CA-4 IC50 1.2 μM [49]. The gene discussed is CA4; the disease is cancer.