First, we evaluated the association of the four DNA methyltransferases with UNC5A expression in pan-cancer and observed that UNC5A was associated with some or all four DNA methytransferases in BLCA, BRCA, CESC, DLBC, GBM, HNSC, KIRC, KIRP, LAML, LGG, LIHC, LUSC, PCPG, PRAD, TGCT, THCA, UCEC, Uterine Carcinosarcoma (UCS), and UVM (Figure 11A). The gene discussed is UNC5A; the disease is uterine carcinosarcoma.