Similarly, in prostate cancer, osteosarcoma, pancreatic cancer and breast cancer, miR-195, miRNA-211-5p, miR-204-5p and miR-144-3p directly targeted PRR11 3′-UTR to participate in cellular activities, including proliferation, migration, cell cycle, apoptosis and angiogenesis [18,56,72,73]. This evidence concerns the gene PRR11 and familial pancreatic carcinoma.