As for its contribution in tumorigenicity, PRR11 facilitates cellular proliferation in vitro in BRCA, Pancreatic cancer and Osteosarcoma; likewise, it contributes to the tumorigenicity of in vitro and in vivo models in TSCC, ESCC, NSCLC, GC, CRC, HCC, HCCA and Ovarian cancer. Here, PRR11 is linked to familial pancreatic carcinoma.