As for its contribution in tumorigenicity, PRR11 facilitates cellular proliferation in vitro in BRCA, Pancreatic cancer and Osteosarcoma; likewise, it contributes to the tumorigenicity of in vitro and in vivo models in TSCC, ESCC, NSCLC, GC, CRC, HCC, HCCA and Ovarian cancer. This evidence concerns the gene PRR11 and hepatocellular carcinoma.