KLK3 and Familial prostate cancer: Interestingly, after grouping patients into PSA levels of above or below 10 ng/mL, there is still significant evidence that a higher PSA level is correlated with higher current values and vice versa (p-value = 0.037), whereas applying the same parameters to miRmiR-21 biomarker to determine prostate cancer staging and age, results were not significant (Table 1).