This finding was supported by Liu et al, and MTURN may serve as a potential biomarker for blood-based lung cancer diagnosis, as well as the prediction of chemotherapy response.[40] The transcriptional regulatory mechanisms between ERG and MTURN, as well as FOXM1 and PTPR, are limited, but our results suggest that ERG-MTURN and FOXM1-PTPR may be regulated by methylation at cg27071152 and cg19212949, respectively. Here, ERG is linked to lung cancer.