BBS10 and Bardet-Biedl syndrome: Among BBS, BBS1 and BBS10 being the most common, and BBS3 being relatively rare accounting for only about 3% of all BBS disease-causing variants.[3] Disease-causing variants in ARL6/BBS3 was first identified as the cause of BBS in a Bedouin tribe in which many consanguineous marriages are traditionally made.[21] BBS with disease-causing ARL6/BBS3 variants is mainly reported in the Middle East[22–25] and La Réunion Island populations.[26] The disease-causing ARL6/BBS3 variants have been reported to account for 18% of all cases of BBS in India.[27]