The 6 prognosis-related genes (CASP8, GRK6, IL3RA, PLCB1, TBKBP1, and TNFSF10) were screened as the most significant indicators, generating the CPRS to assess the patient survival in PRAD (Fig. 4A and B). Here, TBKBP1 is linked to prostate adenocarcinoma.