For instance, lncRNA CASC2 targets miR‐181a/PTEN axis to regulate the proliferation of glioma cells26; lncRNA DLEU2/miR‐186‐5p/PDK3 axis promotes the development of giloma27; and lncRNA SNHG5 enhances the proliferation of glioma cells by regulating miR‐205‐5p/ZEB2 axis expression.28 This evidence concerns the gene ZEB2 and central nervous system cancer.