Growth‐associated protein 43 (GAP‐43) is also an important marker related to the structural integrity of neurons, which is known to promote axonal regeneration by guiding growth cones,58, 59, 60 It was reported that mRNA and protein expressions of GAP‐43 could be increased by RIC in rats after cerebral ischemia.61, 62. The gene discussed is GAP43; the disease is Cerebral ischemia.