NFKB1 and neoplasm: Our study revealed an alternative POSTN/integrin/ERK/NF-κB pathway to promote recruitment of monocytes and differentiation into M2 macrophage-like TAMs in ovarian tumor microenvironment, which could contribute to compromising the tumor immune surveillance through M2 macrophage-associated immune suppressive cytokines (Figs. 5, 7).